The challenges in modern agriculture such as crop diseases, extreme weather, and contamination have spurred interest in Smart Sustainable Agricultural Production (SSAP), which is the use of advanced technologies, innovative management practices, and sustainable methods for efficient and environmentally friendly food production. Our interdisciplinary work aims to develop a novel, multifunctional spray for integrated crop management aligned with SSAP principles to address plant diseases, weed management, and heat injury prevention. The spray will be based on natural, biodegradable formulations incorporating photodynamic inactivation (PDI) chemistries, a light-based technique for cell inactivation through oxidative processes.